Use of hematopoietic cell transplants to achieve tolerance in patients with solid organ transplants.
نویسنده
چکیده
The goals of tolerance in patients with solid organ transplants are to eliminate the lifelong need for immunosuppressive (IS) drugs and to prevent graft loss due to rejection or drug toxicity. Tolerance with complete withdrawal of IS drugs has been achieved in recipients of HLA-matched and mismatched living donor kidney transplants in 3 medical centers using hematopoietic cell transplants to establish mixed or complete chimerism.
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ورودعنوان ژورنال:
- Blood
دوره 127 12 شماره
صفحات -
تاریخ انتشار 2016